IDENTIFICATION OF ANTI-SARS-COV-2 AGENTS BASED ON FLAVOR/FRAGRANCE COMPOSITIONS THAT INHIBIT THE INTERACTION BETWEEN THE VIRUS RECEPTOR BINDING DOMAIN AND HUMAN ANGIOTENSIN CONVERTING ENZYME 2.

Coronavirus disease 2019 (COVID-19) pandemic poses a threat to human beings and numerous cases of infection as well as millions of victims have been reported.The binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein receptor binding domain (RBD) to human angiotensin converting enzyme 2 (hACE2) is known to promote

Architected materials composed of instability-based unit cells have been exploited in energy dissipation/absorption applications.One stability-based unit cell type that comprises slender beams can experience geometrical nonlinearities under small forces.Although reusability provided by these materials is attractive to engineering applications, the

OBJECTIVE: To compare the impact of three strategies for delivering a booster dose of adult-formulated tetanus-diphtheria-pertussis (Tdap) vaccine to adolescents in Australia.These comprise: (i) administering Tdap to: a one-year age cohort; (ii) administering Tdap to the entire high school and to subsequent entrant cohorts; and (iii) administering

We have developed an isotope dilution method for determination of deoxycholic acid pool size and input rate which employs oral administration of 50 mg of [24-13C]deoxycholic acid and serum sampling.The method has been validated by classical isotope dilution technique using [24-14C]deoxycholic acid and bile sampling in five patients with colonic ade